SCHEMBL69537

SCHEMBL69537

O=C(Oc1ccccc1)c1ccccc1-c1ccccc1C(=O)Oc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.68
HPGD P15428 2/20 0.68
ALOX15 P16050 1/20 0.68
MAPT P10636 4/20 0.63
KDM4E B2RXH2 3/20 0.63
TDP1 Q9NUW8 1/20 0.63
ALDH1A1 P00352 5/20 0.56
KMT2A Q03164 2/20 0.56
TSHR P16473 1/20 0.56
LMNA P02545 3/20 0.51
NR4A2 P43354 1/20 0.51
TP53 P04637 1/20 0.51
CYP3A4 P08684 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
CHRM1 P11229 1/20 0.51
TBXA2R P21731 1/20 0.51
SLC6A2 P23975 1/20 0.51
PDE4A P27815 1/20 0.51
ADRA1A P35348 1/20 0.51
KDR P35968 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10346575 0.94 HSD17B10 (0.61) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL3453990 0.90 HSD17B10 (0.61) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL69868 0.89 HSD17B10 (0.76) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL29437924 0.89 HSD17B10 (0.76) HSD17B10HPGDALOX15MAPTKDM4E
Bicarbonate SCHEMBL27452806 0.86 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E
Hydrogen Sulfide SCHEMBL28157119 0.86 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E
Methane SCHEMBL27316738 0.86 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E
Phosphine SCHEMBL28084508 0.86 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL27566769 0.84 HSD17B10 (0.70) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL7551787 0.84 HSD17B10 (0.54) HSD17B10HPGDALOX15MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110435276-A Layered body TEIJIN LTD 2019-11-12 CN disclosed
CN-110248808-A Layered body 帝人株式会社 2019-09-17 CN disclosed
CN-109071789-A Copolycarbonate, using its optical lens and film and the copolymer manufacturing method 三菱瓦斯化学株式会社 2018-12-21 CN disclosed
CN-106661315-B Poly carbonate resin composition 帝人株式会社 2018-11-13 CN disclosed
CN-105713366-B Polycarbonate resin composition and molded article 三菱化学株式会社 2018-08-28 CN disclosed
CN-108350159-A The manufacturing method of resin combination 三菱瓦斯化学株式会社 2018-07-31 CN disclosed
CN-108291016-A Polycarbonate resin, its manufacturing method and film 帝人株式会社 2018-07-17 CN disclosed
CN-108137913-A Resin combination and the film formed by it 帝人株式会社 2018-06-08 CN disclosed
CN-105051089-B Polycarbonate molding product 帝人株式会社 2018-04-03 CN disclosed
CN-103992469-B Polycarbonate and molded article thereof 三菱化学株式会社 2018-03-16 CN disclosed
CN-101435949-A Direct down type backlight liquid crystal display apparatus and light diffusing plate TEIJIN CHEMICALS LTD (JP) 2009-05-20 CN disclosed
EP-1808461-B1 RESIN COMPOSITION AND MOLDED OBJECT THEREOF TEIJIN CHEMICALS LTD (JP) 2009-03-11 EP disclosed
CN-101223460-A Foamed resin sheet and liquid crystal display TEIJIN CHEMICALS LTD (JP) 2008-07-16 CN disclosed
US-20080085955-A1 Resin Composition And Molded Articles Thereof OSAKA GAS CO., LTD. (JP) 2008-04-10 US disclosed
EP-1808461-A1 RESIN COMPOSITION AND MOLDED OBJECT THEREOF Teijin Chemicals, Ltd. (JP) 2007-07-18 EP disclosed
US-4564705-A POLYAMIDE, POLYUREA AND POLYURETHANE MONOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-14 US disclosed
US-4451642-A Bis(aminoneopentyl) aromatics and polyamides derived therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-29 US disclosed
US-4130579-A Bis(2-methyl-2-cyanopropyl) aromatics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-12-19 US disclosed
US-4107444-A INTERMEDIATES FOR POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-08-15 US disclosed
US-4065431-A Thermally stable, rigid polyesters from aromatic dibasic acids and thermally stable, rigid diols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-12-27 US disclosed