Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | HMGCR | P04035 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 17/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329710 | 1.00 | ESR1 (0.48) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL9689998 | 0.90 | GCGR (0.50) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL8973684 | 0.85 | ESR1 (0.62) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL7561153 | 0.85 | ESR1 (0.62) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL9481908 | 0.82 | GCGR (0.47) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL9481915 | 0.82 | GCGR (0.47) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL9482325 | 0.81 | GCGR (0.46) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL6951537 | 0.81 | ESR1 (0.49) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL9689993 | 0.81 | ESR1 (0.49) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL2647866 | 0.81 | GCGR (0.50) | ESR1HMGCRCHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-0325130-B1 | Substituted pyridines | BAYER AG (DE) | 2003-11-05 | — | — | EP | disclosed |
| EP-1123925-A1 | Process for preparation of substituted pyridines | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |
| EP-1123924-A1 | Substituted pyridines as HMG-COA reductase inhibitors | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |
| CN-1274719-A | Process for preparation of substituted pyridine compound | BAYER AG (DE) | 2000-11-29 | — | — | CN | disclosed |
| CN-1055684-C | Process for preparing substituted pyridine compounds | BAYER AG (DE) | 2000-08-23 | — | — | CN | disclosed |
| US-5401746-A | FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND HMG-COA REDUCTASE | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| US-5169857-A | Anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |
| EP-0325130-A2 | Substituted pyridines | BAYER AG (DE) | 1989-07-26 | — | — | EP | disclosed |