Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957110 | 0.92 | MAPK1 (0.62) | MAPK1HTTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6957070 | 0.90 | MAPK1 (0.60) | MAPK1HTTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6949134 | 0.84 | SMN1; SMN2 (0.62) | MAPK1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6952622 | 0.84 | TNF (0.44) | MAPK1KMT2AMEN1RAB9APOLB | |
| SCHEMBL6955465 | 0.82 | MAPK1 (0.59) | MAPK1HTTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6956607 | 0.82 | HTT (0.63) | MAPK1HTTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6955334 | 0.82 | ACKR3 (0.52) | SMN1; SMN2GAACYP2C9HPGDCYP2C19 | |
| SCHEMBL6957506 | 0.81 | MAPK1 (0.58) | MAPK1HTTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6955348 | 0.80 | MAPK1 (0.63) | MAPK1HTTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6957510 | 0.79 | MAPK1 (0.57) | MAPK1HTTKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |