Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.54 |
| ▸ | PPARG | P37231 | 11/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956426 | 0.90 | PPARG (0.59) | PPARAPPARGPPARDTNFALDH1A1 | |
| SCHEMBL6951283 | 0.82 | PPARA (0.54) | PPARAPPARGPPARDALDH1A1KDM4E | |
| SCHEMBL6952900 | 0.79 | TNF (0.48) | PPARAPPARGPPARDTNFALDH1A1 | |
| SCHEMBL7527968 | 0.78 | PPARG (0.82) | PPARAPPARGPPARD | |
| SCHEMBL7527971 | 0.78 | PPARG (0.82) | PPARAPPARGPPARD | |
| SCHEMBL6952391 | 0.77 | PPARG (0.46) | PPARAPPARGPPARDTNFALDH1A1 | |
| SCHEMBL6956161 | 0.77 | PPARG (0.46) | PPARAPPARGPPARDTNFALDH1A1 | |
| SCHEMBL6952396 | 0.77 | MEN1 (0.46) | PPARAPPARGPPARDTNFALDH1A1 | |
| SCHEMBL6953586 | 0.76 | TNF (0.51) | PPARAPPARGPPARDTNFALDH1A1 | |
| SCHEMBL6948934 | 0.76 | MEN1 (0.45) | PPARAPPARGPPARDTNFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |