Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952341 | 0.92 | MEN1 (0.44) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6952404 | 0.81 | TNF (0.46) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6952900 | 0.81 | TNF (0.48) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6956426 | 0.80 | PPARG (0.59) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6955076 | 0.76 | PPARA (0.54) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6952391 | 0.75 | PPARG (0.46) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6956161 | 0.75 | PPARG (0.46) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6952396 | 0.74 | MEN1 (0.46) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6948171 | 0.74 | TNF (0.48) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6953586 | 0.72 | TNF (0.51) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |