Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 11/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932359 | 0.90 | GAA (0.38) | LMNAMAPK1RAB9AGPR119NR1D1 | |
| SCHEMBL2087756 | 0.90 | GAA (0.38) | LMNAMAPK1RAB9AGPR119NR1D1 | |
| SCHEMBL1286879 | 0.82 | PARP1 (0.39) | LMNAMAPK1RAB9AGPR119NR1D1 | |
| SCHEMBL19211629 | 0.81 | GAA (0.44) | LMNAMAPK1RAB9AGPR119GAA | |
| Trifluoroacetic Acid SCHEMBL952417 | 0.76 | SMN1; SMN2 (0.58) | RAB9ADPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL27848482 | 0.75 | HPGD (0.44) | DPP4GPR119 | |
| Trifluoroacetic Acid SCHEMBL18497410 | 0.75 | LMNA (0.45) | LMNAMAPK1RAB9AGPR119HRH4 | |
| SCHEMBL9381172 | 0.75 | SMN1; SMN2 (0.44) | LMNAMAPK1RAB9AGPR119NR1D1 | |
| SCHEMBL9381176 | 0.75 | SMN1; SMN2 (0.44) | LMNAMAPK1RAB9AGPR119NR1D1 | |
| SCHEMBL9389295 | 0.75 | SMN1; SMN2 (0.44) | LMNAMAPK1RAB9AGPR119NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849269-B9 | Vinyl pyrrolidine cephalosporins with basic substituents | BASILEA PHARMACEUTICA AG (CH) | 2003-03-05 | — | — | EP | disclosed |
| US-5981519-A | Vinyl-pyrrolidinone cephalosporins | HOFFMAN-LA ROCHE INC. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0849269-A1 | Vinyl pyrrolidine cephalosporins with basic substituents | F. HOFFMANN-LA ROCHE AG (CH) | 1998-06-24 | — | — | EP | disclosed |