SCHEMBL6955244

SCHEMBL6955244

CCCCC=COC(=O)OC=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 5/20 0.40
F3 P13726 5/20 0.40
TSHR P16473 2/20 0.38
PPARG P37231 5/20 0.38
ALDH1A1 P00352 5/20 0.38
PPARD Q03181 4/20 0.38
PPARA Q07869 4/20 0.38
FFAR1 O14842 3/20 0.38
KDM4E B2RXH2 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP19A1 P11511 2/20 0.38
FABP4 P15090 2/20 0.38
HPGD P15428 2/20 0.38
ALOX15 P16050 2/20 0.38
NR4A2 P43354 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
PTGS1 P23219 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2936006 0.92 F7 (0.45) F7F3TSHRPPARGALDH1A1
SCHEMBL6973672 0.88 ALDH1A1 (0.33) ALDH1A1
SCHEMBL9068845 0.84 PPARG (0.52) F7F3TSHRPPARGALDH1A1
SCHEMBL9069435 0.84 PPARG (0.52) F7F3TSHRPPARGALDH1A1
SCHEMBL18394429 0.84 PPARG (0.52) F7F3TSHRPPARGALDH1A1
SCHEMBL3209628 0.84 PPARG (0.52) F7F3TSHRPPARGALDH1A1
SCHEMBL9070093 0.84 PPARG (0.52) F7F3TSHRPPARGALDH1A1
SCHEMBL6562029 0.84 PPARG (0.52) F7F3TSHRPPARGALDH1A1
SCHEMBL9070097 0.84 PPARG (0.52) F7F3TSHRPPARGALDH1A1
SCHEMBL9070092 0.84 PPARG (0.52) F7F3TSHRPPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed