Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19150283 | 0.94 | DGKA (0.57) | CYP1A2DNM1DGKAKDM5AALDH1A1 | |
| SCHEMBL8399737 | 0.94 | KDM5A (0.53) | CYP1A2DNM1DGKAKDM5AALDH1A1 | |
| SCHEMBL29740738 | 0.94 | CYP1A2 (0.59) | CYP1A2DNM1DGKADRD2ALDH1A1 | |
| SCHEMBL10989917 | 0.92 | DGKA (0.55) | CYP1A2DNM1DGKADRD2KDM5A | |
| SCHEMBL11802987 | 0.92 | DGKA (0.55) | CYP1A2DNM1DGKAKDM5AALDH1A1 | |
| SCHEMBL19478720 | 0.92 | CYP1A2 (0.48) | CYP1A2DNM1DGKADRD2KDM5A | |
| SCHEMBL8466798 | 0.92 | CYP1A2 (0.48) | CYP1A2DNM1DGKADRD2KDM5A | |
| SCHEMBL6844300 | 0.89 | CYP1A2 (0.46) | CYP1A2DNM1DGKADRD2KDM5A | |
| SCHEMBL18831846 | 0.89 | DGKA (0.60) | CYP1A2DNM1DGKAKDM5AALDH1A1 | |
| SCHEMBL22278960 | 0.88 | CYP1A2 (0.53) | CYP1A2DNM1DGKADRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |