Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960387 | 0.91 | KMT2A (0.39) | KMT2AGAAMAPTLMNAALDH1A1 | |
| SCHEMBL6964825 | 0.90 | RBP4 (0.45) | KMT2AGAAMAPTLMNAALDH1A1 | |
| SCHEMBL6960140 | 0.89 | MAPT (0.41) | KMT2AGAAMAPTLMNAALDH1A1 | |
| SCHEMBL6961151 | 0.88 | PHGDH (0.55) | KMT2ALMNAALDH1A1PHGDH | |
| SCHEMBL6953333 | 0.87 | GAA (0.47) | KMT2AGAAMAPTLMNAALDH1A1 | |
| SCHEMBL6954279 | 0.86 | KMT2A (0.49) | KMT2AGAAMAPTLMNAALDH1A1 | |
| SCHEMBL6674803 | 0.86 | PHGDH (0.42) | KMT2AMAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL6961133 | 0.85 | PHGDH (0.39) | KMT2AGAAMAPTLMNAALDH1A1 | |
| SCHEMBL6966881 | 0.85 | KMT2A (0.46) | KMT2AGAAMAPTLMNAALDH1A1 | |
| SCHEMBL6963517 | 0.85 | KMT2A (0.40) | KMT2AGAAMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |