Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6956681 | 0.90 | PPARG (0.40) | PPARGPPARA | |
| SCHEMBL6960249 | 0.85 | PPARG (0.40) | PPARGPPARA | |
| Hydrochloric Acid SCHEMBL6958986 | 0.85 | KDM4E (0.41) | PPARGPPARA | |
| SCHEMBL6959446 | 0.85 | PPARG (0.41) | PPARGPPARAFFAR1 | |
| SCHEMBL6956018 | 0.84 | PPARG (0.40) | PPARGPPARAFFAR1 | |
| Hydrochloric Acid SCHEMBL6960508 | 0.82 | PPARG (0.39) | PPARGPPARAFFAR1 | |
| Hydrochloric Acid SCHEMBL6957244 | 0.82 | ALDH1A1 (0.41) | PPARGPPARAFFAR1 | |
| SCHEMBL6960251 | 0.82 | PPARG (0.39) | PPARGPPARAFFAR1 | |
| Hydrochloric Acid SCHEMBL7657569 | 0.81 | ALDH1A1 (0.41) | PPARGPPARAFFAR1 | |
| SCHEMBL6964581 | 0.79 | PPARG (0.38) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971709-B1 | NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS | LILLY CO ELI (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-0971709-A4 | NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS | LILLY CO ELI (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0971709-A1 | NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS | ELI LILLY AND COMPANY (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1999018091-A1 | NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS | ELI LILLY AND COMPANY (US) | 1999-04-15 | — | — | WO | disclosed |
| EP-0908454-A2 | Oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents | ELI LILLY AND COMPANY (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1998015274-A1 | NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |