Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955860 | 1.00 | KMT2A (0.42) | KMT2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8416346 | 0.86 | ALDH1A1 (0.46) | KMT2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8416348 | 0.86 | ALDH1A1 (0.46) | KMT2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8418119 | 0.86 | ALDH1A1 (0.46) | KMT2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL14719065 | 0.81 | ALDH1A1 (0.43) | KMT2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL1499962 | 0.76 | — | — | |
| SCHEMBL2561552 | 0.76 | — | — | |
| SCHEMBL14744490 | 0.76 | — | — | |
| SCHEMBL14744489 | 0.76 | — | — | |
| SCHEMBL8171660 | 0.76 | KMT2A (0.44) | KMT2AALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023267-B1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL SA (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6482841-B1 | Pyridyl compounds and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2002-11-19 | — | — | US | disclosed |
| EP-1023267-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999019302-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 1999-04-22 | — | — | WO | disclosed |
| US-5177211-A | Anti-platelet aggregation and anti-hypotensive | ALTER, S.A. (ES) | 1993-01-05 | — | — | US | disclosed |
| EP-0325187-B1 | 4-ALKYL-1, 4-DIHYDROPYRIDINES WITH PAF-ANTAGONIST ACTIVITY | ALTER, S.A. (ES) | 1992-11-11 | — | — | EP | disclosed |
| EP-0325187-A1 | 4-alkyl-1, 4-dihydropyridines with PAF-antagonist activity | ALTER, S.A. (ES) | 1989-07-26 | — | — | EP | disclosed |
| US-4727066-A | CARDIOVASCULAR DISORDERS | CERMOL S.A. (CH) | 1988-02-23 | — | — | US | disclosed |
| US-4656181-A | CARDIOTONIC AGENTS | CERMOL S.A. (CH) | 1987-04-07 | — | — | US | disclosed |