Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GLB1 | P16278 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6042465 | 0.83 | KDM4E (0.42) | GBA1PYGLGBA2GAAGLB1 | |
| SCHEMBL2684014 | 0.81 | GBA1 (0.47) | GBA1PYGLGBA2GAAGLB1 | |
| SCHEMBL6958961 | 0.81 | GBA1 (0.47) | GBA1PYGLGBA2GAAGLB1 | |
| Bromide SCHEMBL1941630 | 0.80 | GBA1 (0.46) | GBA1PYGLGBA2GAAGLB1 | |
| Bromide SCHEMBL5282167 | 0.80 | GBA1 (0.46) | GBA1PYGLGBA2GAAGLB1 | |
| SCHEMBL6042903 | 0.80 | GBA1 (0.46) | GBA1PYGLGBA2GAAGLB1 | |
| SCHEMBL27503578 | 0.78 | GBA1 (0.47) | GBA1PYGLGBA2GAAGLB1 | |
| SCHEMBL15984732 | 0.70 | TSHR (0.50) | TP53TSHRP2RY14SRD5A2 | |
| SCHEMBL13831811 | 0.69 | TSHR (0.44) | TP53TSHRP2RY14SRD5A2 | |
| Terephthalic Acid SCHEMBL7753889 | 0.67 | TSHR (0.50) | TP53TSHRSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |