Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28949039 | 0.96 | KMT2A (0.47) | TSHRKMT2ASRD5A2TP53CA1 | |
| Terephthalic Acid SCHEMBL28949037 | 0.96 | KMT2A (0.47) | TSHRKMT2ASRD5A2TP53CA1 | |
| Terephthalic Acid SCHEMBL28949038 | 0.93 | KMT2A (0.45) | TSHRKMT2ASRD5A2TP53CA1 | |
| Terephthalic Acid SCHEMBL28949036 | 0.93 | KMT2A (0.45) | TSHRKMT2ASRD5A2TP53CA1 | |
| SCHEMBL2423060 | 0.85 | CHRNB2 (0.42) | KMT2ASRD5A2ALDH1A1 | |
| Terephthalic Acid SCHEMBL6442298 | 0.82 | KMT2A (0.55) | TSHRKMT2ASRD5A2TP53EPHX1 | |
| Piperonylic Acid SCHEMBL11243067 | 0.79 | ALDH1A1 (0.69) | KMT2ASRD5A2TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL29073826 | 0.79 | TDP1 (0.48) | KMT2AALDH1A1 | |
| Terephthalic Acid SCHEMBL31485057 | 0.78 | TSHR (0.55) | TSHRKMT2ASRD5A2TP53CA1 | |
| Terephthalic Acid SCHEMBL87786 | 0.78 | TSHR (0.55) | TSHRKMT2ASRD5A2TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334385-A1 | FLAME RETARDANT-STABILIZER COMBINATION FOR THERMOPLASTIC POLYMERS | Clariant International Ltd (CH) | 2024-03-13 | — | — | EP | disclosed |
| EP-4301809-A1 | USE OF A STABILIZER COMPOSITION FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, STABILIZER COMPOSITION, MASTER BATCH OR CONCENTRATE, STABILIZED PLASTIC COMPOSITION, PROCESS FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, AND USE OF COMPOSITIONS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2024-01-10 | — | — | EP | disclosed |
| EP-4291605-A1 | COMPOSITIONS COMPRISING AMMONIUM POLYPHOSPHATES | Clariant International Ltd (CH) | 2023-12-20 | — | — | EP | disclosed |
| EP-4271550-A1 | THERMOPLASTIC PULVERULENT COMPOSITION FOR THREE-DIMENSIONAL PRINTING | BASF SE (DE) | 2023-11-08 | — | — | EP | disclosed |
| EP-4247618-A1 | FLAME-RETARDANT PULVERULENT COMPOSITION AND 3D-PRINTED OBJECT OBTAINED FROM THE SAME | BASF SE (DE) | 2023-09-27 | — | — | EP | disclosed |
| EP-4165117-A1 | FLAME RETARDANT-STABILIZER COMBINATION FOR THERMOPLASTIC POLYMERS | Clariant International Ltd (CH) | 2023-04-19 | — | — | EP | disclosed |
| CN-115353724-A | High-infrared-transmission glass fiber reinforced polycarbonate composition and preparation method and application thereof | 金发科技股份有限公司 | 2022-11-18 | — | — | CN | disclosed |
| EP-4025629-A1 | OLIGOMER OR POLYMER, COMPOSITION, USE OF THE OLIGOMER OR POLYMER AND INTERMEDIATE | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2022-07-13 | — | — | EP | disclosed |
| WO-2022144160-A1 | THERMOPLASTIC PULVERULENT COMPOSITION FOR THREE-DIMENSIONAL PRINTING | BASF SE (DE) | 2022-07-07 | — | — | WO | disclosed |
| WO-2022106402-A1 | FLAME-RETARDANT PULVERULENT COMPOSITION AND 3D-PRINTED OBJECT OBTAINED FROM THE SAME | BASF SE (DE) | 2022-05-27 | — | — | WO | disclosed |
| EP-0365469-A1 | Piperidine-triazine compounds for use as stabilizers for organic materials | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |
| EP-0354184-A2 | Compounds containing substituted piperidine groups for use as stabilizers for organic materials | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| EP-0354185-A2 | Piperidine-triazine compounds for use as stabilizers for organic materials | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| EP-0345221-A2 | Polyamines partially substituted by piperidine-triazines | CIBA-GEIGY AG (CH) | 1989-12-06 | — | — | EP | disclosed |
| EP-0345220-A2 | Polyamines partially substituted by bis-piperidyl-triazines | CIBA-GEIGY AG (CH) | 1989-12-06 | — | — | EP | disclosed |
| EP-0327496-A2 | Chemical process | CIBA-GEIGY AG (CH) | 1989-08-09 | — | — | EP | disclosed |
| EP-0313517-A2 | Aliphatic esters of 1,3,2-oxazaphospholidines | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | disclosed |
| EP-0311568-A2 | Long chain N-alykl-alpha-alkyl nitrones and their use as stabilizers | CIBA-GEIGY AG (CH) | 1989-04-12 | — | — | EP | disclosed |
| EP-0309401-A1 | Stabilization of coatings with N-hydroxy hindered amines | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |
| EP-0299925-A1 | Piperidine-triazine compounds for use as stabilizers for organic materials | CIBA-GEIGY AG (CH) | 1989-01-18 | — | — | EP | disclosed |