Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954034 | 0.85 | BACE1 (0.55) | NFE2L2KMT2ALMNAMEN1MAPT | |
| SCHEMBL6954978 | 0.82 | BACE1 (0.68) | NFE2L2KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10666534 | 0.82 | MAOB (0.59) | NFE2L2SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL6960590 | 0.82 | CYP1A2 (0.59) | NFE2L2KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10666536 | 0.82 | MAOB (0.59) | NFE2L2SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL6959842 | 0.82 | MAOB (0.58) | KMT2ALMNAMEN1MAPTAPP | |
| SCHEMBL1431915 | 0.81 | KMT2A (0.58) | NFE2L2KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7660046 | 0.81 | KMT2A (0.58) | NFE2L2KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL30098502 | 0.81 | KMT2A (0.58) | NFE2L2KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1431912 | 0.81 | KMT2A (0.58) | NFE2L2KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023267-B1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL SA (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6482841-B1 | Pyridyl compounds and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2002-11-19 | — | — | US | disclosed |
| EP-1023267-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999019302-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 1999-04-22 | — | — | WO | disclosed |