Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957796 | 0.94 | MAPT (0.35) | P2RX3MAPTKMT2ATP53ALDH1A1 | |
| SCHEMBL6963612 | 0.92 | KMT2A (0.35) | MAPTKMT2ATP53NPSR1MARK3 | |
| SCHEMBL6963615 | 0.92 | KMT2A (0.35) | MAPTKMT2ATP53ALDH1A1KDM4E | |
| SCHEMBL6966508 | 0.88 | KMT2A (0.37) | MAPTKMT2ATP53NPSR1MARK3 | |
| SCHEMBL6957217 | 0.88 | KMT2A (0.35) | MAPTKMT2ATP53NPSR1MARK3 | |
| SCHEMBL6962677 | 0.87 | SLC2A1 (0.40) | MAPTKMT2AALDH1A1NPSR1EGFR | |
| SCHEMBL6962244 | 0.86 | KMT2A (0.35) | P2RX3MAPTKMT2ATP53NPSR1 | |
| SCHEMBL6960905 | 0.86 | KMT2A (0.35) | KMT2ANPSR1MARK3EGFRFYN | |
| SCHEMBL6956604 | 0.86 | KMT2A (0.35) | MAPTKMT2ATP53NPSR1MARK3 | |
| SCHEMBL6961325 | 0.85 | IGF1R (0.34) | MAPTKMT2AALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |