Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963612 | 0.94 | KMT2A (0.35) | KMT2ADRD1TP53MAPTKCNH3 | |
| SCHEMBL6957796 | 0.92 | MAPT (0.35) | KMT2ATP53MAPTPPARAPPARG | |
| SCHEMBL6956604 | 0.92 | KMT2A (0.35) | KMT2ATP53MAPTPPARAPPARG | |
| SCHEMBL6958365 | 0.88 | MAPT (0.38) | KMT2ATP53MAPTPPARAPPARG | |
| SCHEMBL6965486 | 0.88 | KMT2A (0.37) | KMT2ATP53MAPTPPARAPPARG | |
| SCHEMBL6964822 | 0.88 | BRD4 (0.39) | KMT2ATP53MAPTPPARAPPARG | |
| Hydrochloric Acid SCHEMBL6967327 | 0.87 | SMN1; SMN2 (0.34) | KMT2ATP53MAPTEGFRFYN | |
| SCHEMBL6962260 | 0.87 | SLC2A1 (0.40) | KMT2ATP53MAPTKCNH3EGFR | |
| SCHEMBL6963151 | 0.86 | HTR2A (0.35) | KMT2ATP53MAPTPPARAPPARG | |
| SCHEMBL6955926 | 0.86 | P2RX3 (0.34) | KMT2ATP53MAPTEGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |