SCHEMBL725183

SCHEMBL725183

COC(=O)c1ccc2ccccc2n1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
ALDH1A1 P00352 4/20 0.60
HPGD P15428 1/20 0.60
MAPT P10636 3/20 0.59
GAA P10253 1/20 0.59
CNR2 P34972 3/20 0.58
KMT2A Q03164 3/20 0.57
ABCG2 Q9UNQ0 1/20 0.57
KDM4E B2RXH2 3/20 0.56
HTT P42858 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
NFKB1 P19838 1/20 0.56
RAB9A P51151 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
MEN1 O00255 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30208641 1.00 MGAM (0.61) MGAMHDAC8ALDH1A1HPGDMAPT
Hydrochloric Acid SCHEMBL16793838 0.98 MGAM (0.59) MGAMHDAC8ALDH1A1HPGDMAPT
Hydrochloric Acid SCHEMBL30615167 0.98 MGAM (0.59) MGAMHDAC8ALDH1A1HPGDMAPT
Trifluoroacetic Acid SCHEMBL28462831 0.89 MGAM (0.54) MGAMHDAC8ALDH1A1HPGDMAPT
SCHEMBL1742248 0.86 MGAM (0.58) MGAMHDAC8ALDH1A1HPGDMAPT
SCHEMBL3954441 0.85 MGAM (0.66) MGAMHDAC8ALDH1A1HPGDMAPT
SCHEMBL6955948 0.83 MGAM (0.63) MGAMHDAC8ALDH1A1HPGDMAPT
SCHEMBL5176927 0.83 MGAM (0.63) MGAMHDAC8ALDH1A1HPGDMAPT
Dimethylamine SCHEMBL29110933 0.83 MGAM (0.54) MGAMHDAC8ALDH1A1HPGDMAPT
SCHEMBL4303210 0.82 MGAM (0.58) MGAMHDAC8ALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137586-A2 COMPOSITIONS, METHODS, AND SYSTEMS FOR PROMOTING PHOSPHATE SOLUBILIZATION IN PLANTS Tenfold Technologies, LLC (US) 2025-06-26 WO claimed
CN-115947720-B Design, preparation and application of beta 3 adrenergic receptor anchoring probe 南京师范大学 2024-03-29 CN claimed
CN-113880063-B Aluminum removal method for phosphorus iron slag after lithium extraction of waste lithium iron phosphate and preparation method for battery grade iron phosphate 广东光华科技股份有限公司 2023-05-02 CN claimed
CN-115947720-A Design of beta 3 adrenergic receptor anchoring probe and preparation method and application thereof 南京师范大学 2023-04-11 CN claimed
CN-114426534-B Reversible fluorescent probe for detecting copper ions and preparation method thereof 南京师范大学 2023-01-31 CN claimed
CN-110156680-B Preparation method of 4- (dimethoxymethyl) quinoline-2-methyl formate derivative 济南大学 2022-12-30 CN claimed
CN-110156760-B Preparation method of 4- (1, 4-dioxane-2-yl) quinoline-2-methyl formate derivative 济南大学 2022-09-30 CN claimed
CN-114426534-A Reversible fluorescent probe for detecting copper ions and preparation method thereof 南京师范大学 2022-05-03 CN claimed
CN-113880063-A Aluminum removing method for ferrophosphorus slag after lithium extraction of waste lithium iron phosphate and preparation method of battery-grade ferric phosphate 广东光华科技股份有限公司 2022-01-04 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
EP-1412349-A2 PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS Schering Aktiengesellschaft (DE) 2004-04-28 EP claimed
WO-2002098856-A2 PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS SCHERING AKTIENGESELLSCHAFT (DE) 2002-12-12 WO claimed
EP-4701635-A1 1,2,4-TRIAZOLE-3-THIONE INHIBITORS OF TREX2 FOR USE IN THE TREATMENT OF PSORIASIS, ATOPIC DERMATITIS OR ICHTHYOSIS Universitat De Barcelona (ES) 2026-03-04 EP disclosed
EP-4615829-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-09-17 EP disclosed
WO-2025137586-A2 COMPOSITIONS, METHODS, AND SYSTEMS FOR PROMOTING PHOSPHATE SOLUBILIZATION IN PLANTS Tenfold Technologies, LLC (US) 2025-06-26 WO disclosed
US-4525555-A TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS NIPPON OIL COMPANY, LIMITED (JP) 1985-06-25 US disclosed
EP-0052471-A1 Process and catalyst for polymerization of olefins Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-05-26 EP disclosed
US-4330650-A HAVING MAGNESIUM COMPONENTS, TITANIUM COMPONENTS, ORGANOALUMINUM COMPONENTS AND HETEROCYCLIC CARBOXYLIC ESTER ELECTRON DONOR COMPONENTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-05-18 US disclosed
US-4255280-A ORGANOMAGNESIUM, CHLOROSILANE, TITANIUM, ORGANOMETALLIC AND HETEROCYCLIC ESTER COMPONENTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR MGAM 955/4885HDAC8 4787/4885ALDH1A1 4757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.