Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11676455 | 0.89 | TAAR1 (0.41) | TAAR1 | |
| SCHEMBL7043164 | 0.88 | SIGMAR1 (0.41) | TAAR1 | |
| SCHEMBL392681 | 0.82 | AOC3 (0.43) | AOC3ALDH1A1 | |
| SCHEMBL18321215 | 0.82 | KCNH2 (0.44) | TAAR1ALDH1A1 | |
| SCHEMBL11527253 | 0.81 | TAAR1 (0.47) | TAAR1AOC3ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6372344 | 0.81 | TAAR1 (0.47) | TAAR1AOC3ALDH1A1TRPA1RIPK1 | |
| SCHEMBL10972838 | 0.78 | TAAR1 (0.44) | TAAR1AOC3ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5834700 | 0.78 | GRIK1 (0.41) | TAAR1 | |
| SCHEMBL9408793 | 0.76 | TAAR1 (0.42) | TAAR1AOC3CYP1A2CYP2C19 | |
| SCHEMBL6600900 | 0.76 | TAAR1 (0.50) | TAAR1AOC3ALDH1A1TRPA1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-5049576-A | Leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-09-17 | — | — | US | disclosed |