Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7600823 | 0.99 | REN (0.53) | RENALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6961059 | 0.88 | REN (0.62) | REN | |
| SCHEMBL6041877 | 0.83 | MAPT (0.47) | RENALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6041883 | 0.83 | MAPT (0.47) | RENALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7077090 | 0.80 | REN (0.60) | REN | |
| SCHEMBL7078121 | 0.80 | MAPT (0.43) | RENALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6041954 | 0.79 | REN (0.58) | REN | |
| SCHEMBL6041935 | 0.76 | REN (0.68) | REN | |
| SCHEMBL7561042 | 0.74 | REN (0.77) | REN | |
| SCHEMBL6960173 | 0.73 | REN (0.83) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |