Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 8/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957440 | 0.92 | NPC1 (0.61) | NPC1RAB9APKMMITFKMT2A | |
| SCHEMBL6952457 | 0.90 | NPC1 (0.57) | NPC1RAB9APKMMITFKMT2A | |
| SCHEMBL6953763 | 0.89 | NPC1 (0.55) | NPC1RAB9APKMMITFKMT2A | |
| SCHEMBL6954546 | 0.84 | NPC1 (0.59) | NPC1RAB9APKMMITFKMT2A | |
| SCHEMBL6955885 | 0.84 | NPC1 (0.61) | NPC1RAB9APKMMITFKMT2A | |
| SCHEMBL6949134 | 0.84 | SMN1; SMN2 (0.62) | NPC1RAB9AKMT2AMMP2MMP3 | |
| SCHEMBL6956497 | 0.84 | NPC1 (0.58) | NPC1RAB9APKMMITFKMT2A | |
| SCHEMBL6954593 | 0.83 | NPC1 (0.60) | NPC1RAB9APKMMITFKMT2A | |
| SCHEMBL6952622 | 0.83 | TNF (0.44) | RAB9AKMT2APOLBITGB1ITGA4 | |
| SCHEMBL6952445 | 0.83 | NPC1 (0.59) | NPC1RAB9APKMMITFKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |