SCHEMBL6956130

SCHEMBL6956130

CCOC(Cc1ccc(OCCN2CN(c3ccccc3)c3ccc(C)cc3C2=O)cc1)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.46
PPARA Q07869 18/20 0.45
PPARD Q03181 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6955136 0.91 PPARG (0.47) PPARGPPARAPPARD
SCHEMBL6947127 0.87 ALDH1A1 (0.40) PPARGPPARAPPARD
SCHEMBL6947132 0.85 ALDH1A1 (0.41) PPARGPPARAPPARD
SCHEMBL6955247 0.80 MAPT (0.44) PPARGPPARAPPARD
SCHEMBL6952500 0.79 PPARA (0.46) PPARGPPARAPPARD
SCHEMBL8796710 0.76 FFAR1 (0.48) PPARG
SCHEMBL6948643 0.75 PPARG (0.55) PPARGPPARAPPARD
SCHEMBL8301593 0.74 PPARG (0.51) PPARGPPARAPPARD
SCHEMBL8796714 0.74 ALDH1A1 (0.41) PPARG
SCHEMBL6947471 0.71 PPARG (0.45) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903343-B1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP CO LTD (JP) 2003-05-28 EP disclosed
EP-0903343-A1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP Co., Ltd. (JP) 1999-03-24 EP disclosed