⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576897 | 0.80 | — | — | |
| SCHEMBL752269 | 0.79 | — | — | |
| SCHEMBL12868839 | 0.79 | — | — | |
| SCHEMBL12869036 | 0.79 | — | — | |
| SCHEMBL3422966 | 0.76 | CETP (0.39) | — | |
| SCHEMBL18422910 | 0.76 | CETP (0.39) | — | |
| SCHEMBL18422707 | 0.76 | CETP (0.39) | — | |
| SCHEMBL12869182 | 0.73 | — | — | |
| SCHEMBL14944909 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL14297583 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034649-B1 | ALKOXYLATION OF PHENOLIC COMPOUNDS | Conoco Phillips Company (US) | 1985-04-24 | — | — | EP | claimed |
| EP-3762368-B1 | AMINOPYRAZINE DIOL COMPOUNDS AS PI3K-Y INHIBITORS | INCYTE CORP (US) | 2022-01-26 | — | — | EP | disclosed |
| US-11065249-B2 | Diacylglycerol acyl transferase 2 inhibitor | PFIZER INC. (US) | 2021-07-20 | — | — | US | disclosed |
| US-20210100798-A1 | DIACYLGLYCEROL ACYL TRANSFERASE 2 INHIBITOR | PFIZER INC. (US) | 2021-04-08 | — | — | US | disclosed |
| EP-3697789-A1 | CONDENSED IMIDAZOLE DERIVATIVES SUBSTITUTED BY TERTIARY HYDROXY GROUPS AS PI3K-GAMMA INHIBITORS | Incyte Corporation (US) | 2020-08-26 | — | — | EP | disclosed |
| CN-106963514-B | Urinary device | 科洛普拉斯特公司 | 2019-12-17 | — | — | CN | disclosed |
| WO-2019079469-A1 | CONDENSED IMIDAZOLE DERIVATIVES SUBSTITUTED BY TERTIARY HYDROXY GROUPS AS PI3K-GAMMA INHIBITORS | INCYTE CORPORATION (US) | 2019-04-25 | — | — | WO | disclosed |
| EP-3066093-B9 | GSK-3 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-02-07 | — | — | EP | disclosed |
| US-20170352919-A1 | SECONDARY BATTERY-USE ELECTROLYTIC SOLUTION, SECONDARY BATTERY, BATTERY PACK, ELECTRIC VEHICLE, ELECTRIC POWER STORAGE SYSTEM, ELECTRIC POWER TOOL, AND ELECTRONIC APPARATUS | MURATA MANUFACTURING CO., LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
| US-9825338-B2 | Electrolytic solution, non-aqueous secondary battery, battery pack, electric vehicle, electric power storage system, electric power tool, and electronic apparatus | SONY CORPORATION (JP) | 2017-11-21 | — | — | US | disclosed |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007062308-A2 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| EP-1104758-B1 | Acetylene derivatives as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2003-07-23 | — | — | EP | disclosed |
| US-6538009-B2 | Selective cyclooxygenase-2 (COX-2) inhibitors; for example, 1-(5-Methanesulfonyl-pyridin-2-yl)-7-methoxy-3-trifluoromethyl-4,5-dihydro -1H-benzo(g) indazole | PFIZER, INC. | 2003-03-25 | — | — | US | disclosed |
| US-6506779-B1 | useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock. | PFIZER INC. | 2003-01-14 | — | — | US | disclosed |
| US-20020115856-A1 | Pyrazole derivatives as anti-inflammatory/analgesic agents | SAKYA SUBAS MAN (US) | 2002-08-22 | — | — | US | disclosed |
| EP-1142889-A1 | Pyrazole derivatives as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-1104758-A1 | Acetylene derivatives as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| US-3956154-A | AIRCRAFT | STAUFFER CHEMICAL COMPANY (US) | 1976-05-11 | — | — | US | disclosed |