Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558113 | 1.00 | CNR2 (0.65) | CNR2KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL28760324 | 1.00 | CNR2 (0.65) | CNR2KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6953151 | 0.90 | KMT2A (0.71) | CNR2KMT2AUTS2RLMNACNR1 | |
| SCHEMBL6638460 | 0.86 | ITGB3 (0.57) | CNR2SMN1; SMN2HTTHPGDLMNA | |
| SCHEMBL14037327 | 0.86 | ITGB3 (0.57) | CNR2SMN1; SMN2HTTHPGDLMNA | |
| SCHEMBL6983179 | 0.86 | KMT2A (0.54) | CNR2KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5573085 | 0.85 | NR1H4 (0.56) | CNR2KMT2ASMN1; SMN2ALDH1A1HPGD | |
| Ammonia Solution, Strong SCHEMBL4022994 | 0.85 | ITGB3 (0.56) | CNR2SMN1; SMN2HTTHPGDLMNA | |
| Ammonia Solution, Strong SCHEMBL27572931 | 0.85 | ITGB3 (0.56) | CNR2SMN1; SMN2HTTHPGDLMNA | |
| SCHEMBL6827881 | 0.84 | ITGB3 (0.62) | CNR2SMN1; SMN2ALDH1A1HTTNCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1347873-A | (R)-beta-phenylacetylamino-beta-phenylpropionic acid compounds | UNIV SHENYANG PHARMACY (CN) | 2002-05-08 | — | — | CN | claimed |
| EP-1624052-B1 | Process for the production of beta-amino acids with the use of acylase | AJINOMOTO KK (JP) | 2015-05-27 | — | — | EP | disclosed |
| CN-1928102-B | Resolution method of beta-amino acid | ASTATECH CHENGDU PHARMACEUTIACL CO LTD | 2011-08-10 | — | — | CN | disclosed |
| US-7833760-B2 | Process for the production of β-amino acids using acylase | AJINOMOTO CO., INC. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20090258398-A1 | Process for the Production of beta-Amino Acids Using Acylase | NAKAMATSU TSUYOSHI | 2009-10-15 | — | — | US | disclosed |
| US-20090258398-A1 | Process for the Production of beta-Amino Acids Using Acylase | NAKAMATSU TSUYOSHI | 2009-10-15 | — | — | US | disclosed |
| US-7351571-B2 | Process for the production of β-amino acids using acylase | AJINOMOTO CO., INC. (JP) | 2008-04-01 | — | — | US | disclosed |
| CN-1928102-A | Resolution method of beta-amino acid | ASTATECH CHENGDU PHARMACEUTIAC (CN) | 2007-03-14 | — | — | CN | disclosed |
| EP-1021424-B1 | THIADIAZOLE AMIDE MMP INHIBITORS | UPJOHN CO (US) | 2003-02-26 | — | — | EP | disclosed |
| CN-1347873-A | (R)-beta-phenylacetylamino-beta-phenylpropionic acid compounds | UNIV SHENYANG PHARMACY (CN) | 2002-05-08 | — | — | CN | disclosed |
| CN-1347873-A | (R)-beta-phenylacetylamino-beta-phenylpropionic acid compounds | UNIV SHENYANG PHARMACY (CN) | 2002-05-08 | — | — | CN | disclosed |
| CN-1347873-A | (R)-beta-phenylacetylamino-beta-phenylpropionic acid compounds | UNIV SHENYANG PHARMACY (CN) | 2002-05-08 | — | — | CN | disclosed |
| EP-1021424-A1 | THIADIAZOLE AMIDE MMP INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5830869-A | METALLOPROTEASE INHIBITOR | PHARMACIA & UPJOHN COMPANY | 1998-11-03 | — | — | US | disclosed |
| WO-1997048688-A1 | THIADIAZOLE AMIDE MMP INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |