Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681280 | 0.83 | SMN1; SMN2 (0.67) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL2091283 | 0.83 | PAOX (0.60) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL11523231 | 0.83 | PAOX (0.85) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 | |
| Hydrochloric Acid SCHEMBL7427001 | 0.81 | PAOX (0.58) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 | |
| Hydrochloric Acid SCHEMBL1128155 | 0.81 | SMN1; SMN2 (0.64) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL12412725 | 0.81 | PAOX (0.58) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 | |
| Hydrochloric Acid SCHEMBL1127753 | 0.81 | SMN1; SMN2 (0.64) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL1127933 | 0.79 | PAOX (0.56) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL26528338 | 0.79 | PAOX (0.56) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL11715757 | 0.79 | PAOX (0.56) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765160-B1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | UNIV RAMOT (IL) | 2003-04-16 | — | — | EP | claimed |
| US-6096740-A | BLOCK N-METHYL-ASPARTATE | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 2000-08-01 | — | — | US | claimed |
| EP-0765160-A4 | — | — | 1997-04-09 | — | — | EP | claimed |
| EP-0765160-A1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | RAMOT UNIVERSITY, AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 1997-04-02 | — | — | EP | claimed |
| WO-1995020958-A1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 1995-08-10 | — | — | WO | claimed |
| EP-0765160-B1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | UNIV RAMOT (IL) | 2003-04-16 | — | — | EP | disclosed |
| US-6096740-A | BLOCK N-METHYL-ASPARTATE | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 2000-08-01 | — | — | US | disclosed |
| EP-0765160-A4 | — | — | 1997-04-09 | — | — | EP | disclosed |
| EP-0765160-A1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | RAMOT UNIVERSITY, AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995020958-A1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 1995-08-10 | — | — | WO | disclosed |