Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7427001 | 0.98 | PAOX (0.58) | PAOXL3MBTL1TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL28996572 | 0.92 | L3MBTL1 (0.55) | PAOXL3MBTL1TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL30479937 | 0.92 | PAOX (0.72) | PAOXL3MBTL1TSHRALDH1A1HTR7 | |
| SCHEMBL2852219 | 0.89 | L3MBTL1 (0.65) | PAOXL3MBTL1TSHRSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7430675 | 0.87 | L3MBTL1 (0.63) | PAOXL3MBTL1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL5799141 | 0.87 | L3MBTL1 (0.53) | PAOXL3MBTL1TSHRSMN1; SMN2LMNA | |
| SCHEMBL29973082 | 0.85 | L3MBTL1 (0.50) | PAOXL3MBTL1TSHRSMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL8742882 | 0.83 | L3MBTL1 (0.48) | PAOXL3MBTL1TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL11523231 | 0.83 | PAOX (0.85) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL6956288 | 0.83 | PAOX (0.60) | PAOXTSHRSMN1; SMN2CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368650-A1 | 5-(4-FLUOROPHENYL)-2,3-DIHYDRO-1H-IMIDAZO[1,2-A]IMIDAZOLE DERIVATIVES AS ALK INHIBITORS FOR THE TREATMENT OF FIBROSIS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-12-04 | — | — | US | claimed |
| CN-118201915-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2024-06-14 | — | — | CN | claimed |
| EP-3353168-A1 | COMPOUNDS AND METHODS FOR INHIBITING JAK | Dizal (Jiangsu) Pharmaceutical Co., Limited (CN) | 2018-08-01 | — | — | EP | claimed |
| WO-2017050938-A1 | COMPOUNDS AND METHODS FOR INHIBITING JAK | ASTRAZENECA AB (SE) | 2017-03-30 | — | — | WO | claimed |
| EP-1401451-A2 | QUINAZOLINE DERIVATIVES WHICH PROMOTE THE RELEASE OF PARATHYROID HORMONE | Novartis AG (CH) | 2004-03-31 | — | — | EP | claimed |
| WO-2002102782-A2 | QUINAZOLINE DERIVATIVES which PROMOTE THE RELEASE OF PARATHYROID_HORMONE | NOVARTIS AG (CH) | 2002-12-27 | — | — | WO | claimed |
| WO-2000014109-A1 | BASIC PRODUCTS HAVING ANTAGONISTIC ACTIVITY ON THE NK-1 RECEPTOR AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | MENARINI RICERCHE S.P.A. (IT) | 2000-03-16 | — | — | WO | claimed |
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | claimed |
| US-20250368650-A1 | 5-(4-FLUOROPHENYL)-2,3-DIHYDRO-1H-IMIDAZO[1,2-A]IMIDAZOLE DERIVATIVES AS ALK INHIBITORS FOR THE TREATMENT OF FIBROSIS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-12-04 | — | — | US | disclosed |
| US-20250269050-A1 | CYCLIC DICHALCOGENIDE ADC LINKER UNITS AND USES THEREOF | THORN SESHOLD OLIVER (DE) | 2025-08-28 | — | — | US | disclosed |
| CN-118201915-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-115427032-A | Pharmaceutical composition and use thereof | 浙江养生堂天然药物研究所有限公司 | 2022-12-02 | — | — | CN | disclosed |
| WO-2020232056-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-11-19 | — | — | WO | disclosed |
| EP-2507232-B1 | PROLINE DERIVATIVES | NATIONAL HEALTH RES INST (TW) | 2019-03-20 | — | — | EP | disclosed |
| US-20090281072-A1 | Diaminopyrimidinecarboxamide Derivative | ASTELLAS PHARM INC. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-7449456-B2 | Diaminopyrimidinecarboxamide derivative | ASTELLAS PHARMA, INC. (JP) | 2008-11-11 | — | — | US | disclosed |
| EP-1401451-A2 | QUINAZOLINE DERIVATIVES WHICH PROMOTE THE RELEASE OF PARATHYROID HORMONE | Novartis AG (CH) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002102782-A2 | QUINAZOLINE DERIVATIVES which PROMOTE THE RELEASE OF PARATHYROID_HORMONE | NOVARTIS AG (CH) | 2002-12-27 | — | — | WO | disclosed |
| WO-2000014109-A1 | BASIC PRODUCTS HAVING ANTAGONISTIC ACTIVITY ON THE NK-1 RECEPTOR AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | MENARINI RICERCHE S.P.A. (IT) | 2000-03-16 | — | — | WO | disclosed |
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250368650-A1 | 5-(4-FLUOROPHENYL)-2,3-DIHYDRO-1H-IMIDAZO[1,2-A]IMIDAZOLE DERIVATIVES AS ALK INHIBITORS FOR THE TREATMENT OF FIBROSIS | ALK, TGFBR2, TGFBR1 | PAOX 1528/4885L3MBTL1 4590/4885TSHR 649/4885 |
| US-20250269050-A1 | CYCLIC DICHALCOGENIDE ADC LINKER UNITS AND USES THEREOF | CCL2, UACA, CAD | PAOX 3513/4885L3MBTL1 2632/4885TSHR 1876/4885 |
| US-20090281072-A1 | Diaminopyrimidinecarboxamide Derivative | STAT6, STAT4, STAT3 | PAOX 1930/4885L3MBTL1 1229/4885TSHR 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.