Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 3/20 | 0.63 |
| ▸ | CTSS | P25774 | 16/20 | 0.57 |
| ▸ | CTSL | P07711 | 13/20 | 0.40 |
| ▸ | CTSB | P07858 | 13/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL697466 | 0.92 | CTSS (0.58) | CTSCCTSSCTSLCTSBCTSK | |
| SCHEMBL2106602 | 0.83 | CTSC (0.55) | CTSCCTSSCTSLCTSBCTSK | |
| Hydrochloric Acid SCHEMBL2105547 | 0.82 | CTSC (0.54) | CTSCCTSSCTSLCTSBCTSK | |
| SCHEMBL15193990 | 0.80 | CTSS (0.62) | CTSCCTSSCTSLCTSBCTSK | |
| SCHEMBL15194658 | 0.78 | CTSS (0.62) | CTSCCTSSCTSLCTSB | |
| SCHEMBL29840821 | 0.77 | CTSC (1.00) | CTSCCTSSCTSLCTSBCTSK | |
| SCHEMBL695789 | 0.77 | CTSS (0.63) | CTSCCTSSCTSLCTSB | |
| SCHEMBL694339 | 0.77 | CTSS (0.71) | CTSCCTSSCTSLCTSB | |
| SCHEMBL696268 | 0.77 | CTSS (0.63) | CTSCCTSSCTSLCTSB | |
| Hydrochloric Acid SCHEMBL695404 | 0.76 | CTSS (0.62) | CTSCCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421826-A1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2012-02-29 | — | — | EP | disclosed |