Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL6962843 | 0.84 | HTR1F (0.67) | HTR1FKMT2AMEN1SMN1; SMN2HTR1B | |
| SCHEMBL7664459 | 0.83 | HTR1F (0.79) | HTR1FKMT2AMEN1SMN1; SMN2HTR1B | |
| SCHEMBL7657208 | 0.82 | HTR1F (0.72) | HTR1FKMT2AMEN1SMN1; SMN2HTR1B | |
| Hydrochloric Acid SCHEMBL6963197 | 0.82 | HTR1F (0.68) | HTR1FKMT2AMEN1SMN1; SMN2HTR1B | |
| SCHEMBL6959010 | 0.81 | HTR1F (0.65) | HTR1FKMT2AMEN1SMN1; SMN2HTR1B | |
| Hydrochloric Acid SCHEMBL6954125 | 0.81 | HTR1F (0.67) | HTR1FKMT2AMEN1SMN1; SMN2HTR1B | |
| SCHEMBL7665368 | 0.81 | HTR1F (1.00) | HTR1FKMT2AMEN1SMN1; SMN2HTR1B | |
| SCHEMBL8110900 | 0.81 | HTR1F (1.00) | HTR1FKMT2AMEN1SMN1; SMN2HTR1B | |
| SCHEMBL7666368 | 0.80 | HTR1F (0.69) | HTR1FKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9333438 | 0.80 | HTR1F (0.68) | HTR1FKMT2AMEN1SMN1; SMN2HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882726-B1 | Carbazol-carboxamides as 5-HT1F agonists | LILLY CO ELI (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6221884-B1 | Carboxamides useful as 5-HT1F agonists | ELI LILLY AND COMPANY | 2001-04-24 | — | — | US | disclosed |
| EP-0882726-A1 | Carbazol-carboxamides as 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |