Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949857 | 0.91 | PRKAA2 (0.47) | GCGRKDM4ELMNAHPGDMAPT | |
| SCHEMBL6961082 | 0.89 | GCGR (0.47) | GCGRPRKAA2 | |
| SCHEMBL6961105 | 0.88 | GCGR (0.50) | GCGR | |
| SCHEMBL6961362 | 0.85 | GCGR (0.35) | GCGRPRKAA2 | |
| SCHEMBL6953892 | 0.81 | GCGR (0.61) | GCGR | |
| SCHEMBL6962775 | 0.80 | GCGR (0.48) | GCGR | |
| SCHEMBL9273566 | 0.80 | GCGR (0.50) | GCGRKDM4ELMNAHPGDHTT | |
| SCHEMBL6961920 | 0.80 | GCGR (0.51) | GCGR | |
| SCHEMBL6958555 | 0.79 | GCGR (0.61) | GCGR | |
| SCHEMBL6963303 | 0.79 | GCGR (0.50) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325130-B1 | Substituted pyridines | BAYER AG (DE) | 2003-11-05 | — | — | EP | disclosed |
| EP-1123925-A1 | Process for preparation of substituted pyridines | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |
| EP-1123924-A1 | Substituted pyridines as HMG-COA reductase inhibitors | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |
| EP-0325130-A2 | Substituted pyridines | BAYER AG (DE) | 1989-07-26 | — | — | EP | disclosed |