Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.57 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.49 |
| ▸ | AVPR1B | P47901 | 8/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | MTTP | P55157 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970609 | 0.93 | AVPR1A (0.54) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL6960423 | 0.86 | AVPR2 (0.58) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL6964451 | 0.84 | AVPR1A (0.49) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6972489 | 0.81 | AVPR2 (0.63) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6970821 | 0.81 | AVPR1A (0.57) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL6968185 | 0.79 | AVPR1A (0.54) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL6957855 | 0.79 | AVPR1A (0.54) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL6970491 | 0.78 | AVPR2 (0.61) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL6965230 | 0.77 | AVPR1A (0.56) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL6968346 | 0.77 | HSD11B1 (0.41) | AVPR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |