Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM6A | O15550 | 1/20 | 0.46 |
| ▸ | TET3 | O43151 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KDM4B | O94953 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16915055 | 0.84 | KDM4E (0.50) | POLBNCOA1NCOA3TSHRCYP1A2 | |
| SCHEMBL3037149 | 0.81 | POLB (0.54) | POLBNCOA1NCOA3TSHRCYP1A2 | |
| SCHEMBL6958597 | 0.80 | NCOA1 (0.47) | POLBNCOA1NCOA3TSHRCYP1A2 | |
| SCHEMBL2127197 | 0.78 | KDM4E (0.59) | TSHRKDM4EL3MBTL1KDM6BKDM6A | |
| SCHEMBL12130370 | 0.78 | CYP1A2 (0.54) | POLBNCOA1NCOA3TSHRCYP1A2 | |
| SCHEMBL1982991 | 0.78 | ALDH1A1 (0.59) | POLBNCOA1NCOA3TSHRCYP1A2 | |
| SCHEMBL12101490 | 0.78 | POLB (0.54) | POLBNCOA1NCOA3TSHRCYP1A2 | |
| SCHEMBL4079065 | 0.78 | POLB (0.54) | POLBNCOA1NCOA3TSHRCYP1A2 | |
| SCHEMBL8381644 | 0.78 | POLB (0.54) | POLBNCOA1NCOA3TSHRCYP1A2 | |
| SCHEMBL31233910 | 0.78 | POLB (0.54) | POLBNCOA1NCOA3TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164119-A | 5-amino-quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists | SUVEN LIFE SCIENCES LTD | 2015-12-16 | — | — | CN | disclosed |
| WO-2015107133-A1 | QUINOLINE DERIVATIVES AS INSECTICIDES AND ACARICIDES | BAYER CROPSCIENCE AG (DE) | 2015-07-23 | — | — | WO | disclosed |
| EP-0931070-B1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AG (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-6479436-B1 | SUCH AS 2-(8-BROMOQUINOLIN-5-YL)CARBONYL-1,3-CYCLOHEXANEDIONE | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-12 | — | — | US | disclosed |
| US-6262074-B1 | 4-Hetaroylpyrazol derivatives and the use thereof as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |
| CN-1235600-A | 4-hetaroylpyrazol derivatives | BASF AG (DE) | 1999-11-17 | — | — | CN | disclosed |
| CN-1230951-A | Herbicidal heteroaroyl cyclohexanedione derivatives | BASF AG (DE) | 1999-10-06 | — | — | CN | disclosed |
| EP-0931070-A1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-28 | — | — | EP | disclosed |
| EP-0929546-A1 | 4-HETAROYLPYRAZOL DERIVATIVES AND THE USE THEREOF AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998012180-A1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-26 | — | — | WO | disclosed |
| WO-1998012192-A1 | 4-HETAROYLPYRAZOL DERIVATIVES AND THE USE THEREOF AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-26 | — | — | WO | disclosed |