Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.55 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960853 | 0.77 | CSNK2A2 (0.64) | CSNK2A2CSNK2A1NPY5RTNIKCHRNA3 | |
| SCHEMBL13312218 | 0.77 | APP (0.65) | CSNK2A2CSNK2A1NPY5RTNIKCHRNA3 | |
| SCHEMBL7930564 | 0.75 | CSNK2A2 (0.65) | CSNK2A2CSNK2A1NPY5RCHRNA3KCNH2 | |
| SCHEMBL1666395 | 0.74 | CSNK2A2 (0.90) | CSNK2A2CSNK2A1NPY5RTNIKCHRNA3 | |
| SCHEMBL6395915 | 0.73 | CSNK2A2 (0.58) | CSNK2A2CSNK2A1NPY5RCHRNA3KCNH2 | |
| SCHEMBL1664964 | 0.73 | CSNK2A2 (0.88) | CSNK2A2CSNK2A1NPY5RTNIKCHRNA3 | |
| SCHEMBL7000363 | 0.72 | NPY5R (1.00) | CSNK2A2CSNK2A1NPY5RCHRNA3KCNH2 | |
| SCHEMBL21262532 | 0.72 | CSNK2A2 (0.64) | CSNK2A2CSNK2A1NPY5RTNIKMEN1 | |
| SCHEMBL21262534 | 0.72 | TNIK (0.70) | CSNK2A2CSNK2A1NPY5RTNIK | |
| SCHEMBL29965727 | 0.72 | TNIK (0.70) | CSNK2A2CSNK2A1NPY5RTNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |
| US-6043246-A | Urea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-28 | — | — | US | claimed |
| EP-0955293-A1 | NOVEL UREA DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-10 | — | — | EP | claimed |
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6043246-A | Urea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0955293-A1 | NOVEL UREA DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-10 | — | — | EP | disclosed |