Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.50 |
| ▸ | PPARA | Q07869 | 16/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960726 | 0.94 | KDR (0.50) | PPARGPPARA | |
| SCHEMBL6965683 | 0.90 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL4283015 | 0.87 | PPARG (0.63) | PPARGPPARACYP3A4CYP2C9PPARD | |
| SCHEMBL170065 | 0.87 | PPARG (0.63) | PPARGPPARACYP3A4CYP2C9PPARD | |
| SCHEMBL6959897 | 0.86 | KDR (0.47) | PPARGPPARA | |
| SCHEMBL6954966 | 0.85 | FFAR1 (0.49) | PPARGPPARACYP3A4CYP2C9 | |
| SCHEMBL6956104 | 0.85 | FFAR1 (0.47) | PPARGPPARACYP3A4CYP2C9 | |
| SCHEMBL6954182 | 0.85 | FFAR1 (0.49) | PPARGPPARAPPARD | |
| SCHEMBL6052105 | 0.84 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL6965144 | 0.82 | FFAR1 (0.50) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |