Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20825754 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ADPP4 | |
| SCHEMBL15447182 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ADPP4 | |
| SCHEMBL685371 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ADPP4 | |
| SCHEMBL26478517 | 0.88 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ADPP4 | |
| SCHEMBL12493728 | 0.86 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ADPP4 | |
| SCHEMBL14404904 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL30759407 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14382174 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14351217 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL15184308 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| US-7820671-B2 | Hepatitis C antiviral agents including telaprevir (VX 950); higher tolerance, reduced side effects; azaheterocyclic amido ketone derivatives | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-10-26 | — | — | US | disclosed |
| CN-101460494-A | Process for production of 4-substituted azetidinone derivatives | KANEGAFUCHI CHEMICAL IND (JP) | 2009-06-17 | — | — | CN | disclosed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |