Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954234 | 0.86 | STAT3 (0.47) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL7471382 | 0.85 | TOP2A (0.44) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL1343268 | 0.82 | GSK3B (0.58) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL6957895 | 0.81 | KCNH2 (0.42) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL500863 | 0.80 | GSK3B (0.64) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL5783269 | 0.78 | GSK3B (0.51) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL502617 | 0.78 | GSK3B (0.51) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL12131079 | 0.78 | GSK3B (0.62) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8619910 | 0.77 | GSK3B (0.39) | GSK3BCACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL4671194 | 0.76 | CHRM1 (0.37) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0900793-B1 | CYCLOALKYLAMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-6194434-B1 | MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-0900793-A1 | CYCLOALKYLAMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |