Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971630 | 0.98 | ACHE (0.65) | ACHEEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11810518 | 0.98 | ACHE (0.65) | ACHEEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3627549 | 0.94 | ACHE (0.58) | ACHEEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6539526 | 0.86 | ACHE (0.50) | ACHEEPHX1 | |
| SCHEMBL19506600 | 0.83 | ACHE (0.59) | ACHEEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5546852 | 0.82 | ACHE (0.68) | ACHEEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19506292 | 0.81 | ACHE (0.62) | ACHEEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7351676 | 0.81 | ACHE (0.67) | ACHEEPHX1 | |
| SCHEMBL6688659 | 0.80 | ACHE (0.56) | ACHEEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28167774 | 0.80 | ACHE (0.61) | ACHEEPHX1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |