Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 18/20 | 0.71 |
| ▸ | CA9 | Q16790 | 17/20 | 0.71 |
| ▸ | ELANE | P08246 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 5/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290946 | 0.87 | CA12 (0.69) | CA12CA9ELANECA2CA1 | |
| SCHEMBL356403 | 0.83 | CA12 (0.69) | CA12CA9ELANECA2 | |
| SCHEMBL30834902 | 0.83 | CA12 (1.00) | CA12CA9ELANECA2CA1 | |
| SCHEMBL30657571 | 0.83 | CA12 (0.69) | CA12CA9ELANECA2CA1 | |
| SCHEMBL5899155 | 0.83 | ELANE (1.00) | CA12CA9ELANECA2CA1 | |
| SCHEMBL8865776 | 0.83 | CA12 (0.69) | CA12CA9ELANECA2CA1 | |
| SCHEMBL7281348 | 0.83 | CA12 (0.69) | CA12CA9ELANECA2CA1 | |
| SCHEMBL1101896 | 0.83 | CA12 (1.00) | CA12CA9ELANECA2CA1 | |
| SCHEMBL7290973 | 0.83 | CA12 (0.69) | CA12CA9ELANECA2CA1 | |
| SCHEMBL7932914 | 0.82 | CA9 (0.74) | CA12CA9ELANECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848004-B1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2003-04-02 | — | — | EP | claimed |
| EP-0848004-B1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5955616-A | PROSTAGLANDIN INHIBITORS | SHIONOGI & CO., LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0848004-A1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |