SCHEMBL356403

SCHEMBL356403

O=C1c2ccccc2S(=O)(=O)N1CO

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA12 O43570 15/20 0.69
CA9 Q16790 13/20 0.69
ELANE P08246 2/20 0.69
CA2 P00918 6/20 0.68
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
POLB P06746 1/20 0.60
GAA P10253 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9831972 0.86 CA12 (0.71) CA12CA9ELANECA2NPC1
SCHEMBL6958970 0.83 CA12 (0.71) CA12CA9ELANECA2
SCHEMBL17329453 0.82 CA9 (0.73) CA12CA9ELANECA2
SCHEMBL7281348 0.81 CA12 (0.69) CA12CA9ELANECA2
SCHEMBL5899155 0.81 ELANE (1.00) CA12CA9ELANECA2
SCHEMBL7290973 0.81 CA12 (0.69) CA12CA9ELANECA2
SCHEMBL1101896 0.81 CA12 (1.00) CA12CA9ELANECA2
SCHEMBL7290946 0.81 CA12 (0.69) CA12CA9ELANECA2
SCHEMBL8865776 0.81 CA12 (0.69) CA12CA9ELANECA2
SCHEMBL30834902 0.81 CA12 (1.00) CA12CA9ELANECA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968751-B2 Method of fluorination MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-06-28 US claimed
EP-2189466-A2 METHOD OF FLUORINATION BY MICROWAVES Mitsubishi Gas Chemical Company, Inc. (JP) 2010-05-26 EP claimed
US-20080319228-A1 Method of fluorination HARA SHOJI 2008-12-25 US claimed
EP-0106772-B1 THERMOGRAPHIC COMPOSITIONS CONTAINING THESE DEVELOPERS AND THERMOGRAPHIC COPYING MATERIALS AUSSEDAT-REY (FR) 1987-03-25 EP claimed
US-4536219-A SACCHARIN DERIVATIVES AS DEVELOPERS SOCIETE ANONYME: AUSSEDAT-REY (FR) 1985-08-20 US claimed
WO-2025260159-A1 ISOINDOLINE AND INDOLINE DERIVATIVE COMPOUNDS, COMBINATIONS, PHARMACEUTICAL COMPOSITIONS, MEDICAMENTS, USE OF THE COMPOUNDS AND METHOD OF TREATMENT OF PAIN MICROBIOLÓGICA QUÍMICA E FARMACÊUTICA LTDA. (BR) 2025-12-26 WO disclosed
CN-103328400-B Glass fiber bundling agent and glass fiber reinforced crystalline resin composition ADEKA CORP. (JP) 2015-12-02 CN disclosed
US-8980163-B2 Process for producing plastic bottle ADEKA CORPORATION (JP) 2015-03-17 US disclosed
EP-2423260-B1 PROCESS FOR PRODUCING PLASTIC BOTTLE ADEKA CORP (JP) 2013-12-04 EP disclosed
CN-103328400-A Glass fiber bundling agent and glass fiber reinforced crystalline resin composition ADEKA CORP 2013-09-25 CN disclosed
EP-2423260-A1 PROCESS FOR PRODUCING PLASTIC BOTTLE Adeka Corporation (JP) 2012-02-29 EP disclosed
US-20120013049-A1 PROCESS FOR PRODUCING PLASTIC BOTTLE ADEKA CORPORATION (JP) 2012-01-19 US disclosed
EP-0483928-A1 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use STERLING WINTHROP INC. (US) 1992-05-06 EP disclosed
EP-0471756-A4 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF 1992-04-08 EP disclosed
EP-0471756-A1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF. STERLING WINTHROP INC (US) 1992-02-26 EP disclosed
EP-0253092-B1 1,4-DIHYDROPYRIDINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTITHROMBOTIC DRUGS ALTER, S.A. (ES) 1991-09-25 EP disclosed
WO-1990013549-A1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF STERLING WINTHROP INC. (US) 1990-11-15 WO disclosed
US-4782069-A INHIBITION OF PLATELET ACTIVATION ALTER, S.A. (ES) 1988-11-01 US disclosed
US-4629683-A STORAGE STABILITY AND TIMELY RELEASE OF PHOTOGRAPHICALLY USEFUL AGENT FUJI PHOTO FILM CO., LTD. (JP) 1986-12-16 US disclosed
US-4536219-A SACCHARIN DERIVATIVES AS DEVELOPERS SOCIETE ANONYME: AUSSEDAT-REY (FR) 1985-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319228-A1 Method of fluorination FUCA2, FABP2, FGB CA12 119/4885CA9 689/4885ELANE 2066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.