Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.37 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.37 |
| ▸ | MCHR2 | Q969V1 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL914747 | 0.99 | MCHR1 (0.36) | MCHR1KCNH2MLLT1MCHR2HTR7 | |
| SCHEMBL915514 | 0.95 | MLLT1 (0.37) | MCHR1KCNH2MLLT1MCHR2HTR7 | |
| SCHEMBL6962916 | 0.93 | ALDH1A1 (0.40) | MCHR1KCNH2HTR7KMT2AALDH1A1 | |
| SCHEMBL6962655 | 0.93 | MAOB (0.37) | KMT2AALDH1A1 | |
| SCHEMBL13593469 | 0.93 | MAOB (0.37) | KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL915729 | 0.92 | ALDH1A1 (0.39) | MCHR1KCNH2HTR7KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL914376 | 0.92 | MAOB (0.36) | KMT2AALDH1A1 | |
| SCHEMBL6959397 | 0.92 | SLC2A1 (0.35) | MCHR1KCNH2MLLT1MCHR2HTR7 | |
| SCHEMBL913973 | 0.92 | MAOB (0.43) | MCHR1KCNH2KMT2AALDH1A1 | |
| SCHEMBL13593470 | 0.92 | MAOB (0.43) | MCHR1KCNH2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183366-B2 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2012-05-22 | — | — | US | disclosed |
| US-8183366-B2 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2012-05-22 | — | — | US | disclosed |
| US-20110015180-A1 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2011-01-20 | — | — | US | disclosed |
| US-20110015180-A1 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2011-01-20 | — | — | US | disclosed |
| US-7858781-B2 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2010-12-28 | — | — | US | disclosed |
| US-7858781-B2 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2010-12-28 | — | — | US | disclosed |
| US-20070155721-A1 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2007-07-05 | — | — | US | disclosed |
| US-20070155721-A1 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015180-A1 | Chemokine receptor antagonists | ACKR3, CXCR2, CXCR4 | MCHR1 257/4885KCNH2 2612/4885MLLT1 4437/4885 |
| US-20070155721-A1 | Chemokine receptor antagonists | ACKR3, CXCR2, CXCR4 | MCHR1 246/4885KCNH2 2554/4885MLLT1 4447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.