SCHEMBL6959190

SCHEMBL6959190

Cc1ccc(CSS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 10/20 0.83
ACHE P22303 10/20 0.83
G6PD P11413 2/20 0.63
GAA P10253 2/20 0.52
DNMT1 P26358 1/20 0.52
ALDH1A1 P00352 4/20 0.50
RECQL P46063 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11292921 0.91 BCHE (1.00) BCHEACHEG6PDGAAALDH1A1
SCHEMBL11854518 0.91 BCHE (1.00) BCHEACHEG6PDALDH1A1
SCHEMBL11858241 0.91 BCHE (1.00) BCHEACHEG6PDGAAALDH1A1
SCHEMBL11607679 0.91 BCHE (1.00) BCHEACHEG6PDGAADNMT1
SCHEMBL6954550 0.88 ACHE (1.00) BCHEACHEG6PDALDH1A1
SCHEMBL8434487 0.84 BCHE (0.76) BCHEACHEG6PDDNMT1HTT
SCHEMBL19785990 0.84 BCHE (0.70) BCHEACHEG6PDDNMT1ALDH1A1
SCHEMBL28860080 0.83 BCHE (0.62) BCHEACHEG6PDALDH1A1MEN1
SCHEMBL19785998 0.82 BCHE (0.68) BCHEACHEG6PDDNMT1ALDH1A1
SCHEMBL6956157 0.81 BCHE (0.74) BCHEACHECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018012947-A1 NOVEL ORGANIC SULFUR COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER OR AN INFLAMMATORY DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT 숙명여자대학교 산학협력단 2018-01-18 WO disclosed
EP-0729465-B1 PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS PARKE DAVIS & CO (US) 2003-01-22 EP disclosed
US-6005103-A TREATMENT OF BACTERIAL AND VIRAL INFECTIONS AND DISEASES, INCLUDING AIDS WARNER-LAMBERT COMPANY (US) 1999-12-21 US disclosed
US-5808062-A AIDS THERAPY WARNER-LAMBERT COMPANY (US) 1998-09-15 US disclosed
US-3943176-A PLANT GROWTH REGULATOR THE DOW CHEMICAL COMPANY (US) 1976-03-09 US disclosed