SCHEMBL6959226

SCHEMBL6959226

COc1ccccc1CO[C@H]1CNC[C@@H](O)[C@@H]1c1ccc(OCCCOCc2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6041461 0.92 REN (0.66) REN
SCHEMBL6043306 0.90 REN (0.61) REN
SCHEMBL6042521 0.89 REN (0.80) REN
SCHEMBL6041668 0.89 REN (0.80) REN
SCHEMBL6043274 0.88 REN (0.72) REN
SCHEMBL6041494 0.88 REN (0.59) REN
SCHEMBL6042251 0.88 REN (0.67) REN
SCHEMBL6041869 0.88 REN (0.67) REN
SCHEMBL6042923 0.87 REN (0.56) REN
SCHEMBL7443015 0.87 REN (0.56) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863875-B1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY HOFFMANN LA ROCHE (CH) 2003-06-04 EP claimed