Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954988 | 0.96 | REN (0.46) | RENPDE4BL3MBTL1 | |
| SCHEMBL6956178 | 0.92 | REN (0.48) | RENPDE4B | |
| SCHEMBL6955160 | 0.91 | REN (0.50) | RENL3MBTL1 | |
| SCHEMBL6959740 | 0.90 | REN (0.46) | RENPDE4BL3MBTL1 | |
| SCHEMBL7077322 | 0.89 | REN (0.62) | REN | |
| SCHEMBL6956038 | 0.89 | REN (0.48) | RENPDE4BL3MBTL1 | |
| SCHEMBL6959373 | 0.89 | REN (0.51) | RENL3MBTL1 | |
| SCHEMBL7082878 | 0.88 | REN (0.50) | RENL3MBTL1 | |
| SCHEMBL6953562 | 0.88 | REN (0.51) | REN | |
| SCHEMBL6951457 | 0.88 | REN (0.45) | RENPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |