Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 4/20 | 0.57 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20225729 | 1.00 | PDCD1 (0.57) | PDCD1CD274CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL12764476 | 0.94 | MAPT (0.53) | PDCD1CD274ALDH1A1USP2LMNA | |
| SCHEMBL18101270 | 0.94 | MAPT (0.53) | PDCD1CD274ALDH1A1USP2LMNA | |
| SCHEMBL16559901 | 0.94 | MAPT (0.53) | PDCD1CD274ALDH1A1USP2LMNA | |
| SCHEMBL18101275 | 0.94 | MAPT (0.53) | PDCD1CD274ALDH1A1USP2LMNA | |
| SCHEMBL14787738 | 0.94 | MAPT (0.53) | PDCD1CD274ALDH1A1USP2LMNA | |
| SCHEMBL3083264 | 0.92 | PDCD1 (0.50) | PDCD1CD274CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL20225724 | 0.91 | CD274 (0.54) | PDCD1CD274CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL15853566 | 0.90 | PDCD1 (0.49) | PDCD1CD274CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL16472555 | 0.90 | PDCD1 (0.49) | PDCD1CD274CYP2D6CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113559904-B | Application of nitrogen-carbon material anchored iron single-atom catalyst in catalyzing ammoxidation of alcohol to prepare nitrile | 南京理工大学 | 2024-04-02 | — | — | CN | claimed |
| EP-4665718-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2025-12-24 | — | — | EP | disclosed |
| US-RE50453-E1 | Indole derivatives as CFTR modulators | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-10 | — | — | US | disclosed |
| WO-2024168426-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | APOGEE PHARMACEUTICALS, INC. (CA) | 2024-08-22 | — | — | WO | disclosed |
| CN-113559904-B | Application of nitrogen-carbon material anchored iron single-atom catalyst in catalyzing ammoxidation of alcohol to prepare nitrile | 南京理工大学 | 2024-04-02 | — | — | CN | disclosed |
| US-20240092766-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2024-03-21 | — | — | US | disclosed |
| CN-114539231-B | Glycoside derivative and preparation method and application thereof | 北京盈科瑞创新药物研究有限公司 | 2023-11-21 | — | — | CN | disclosed |
| US-11795165-B2 | Tetrahydro-benzoazepine glycosidase inhibitors | ASCENEURON SA (CH) | 2023-10-24 | — | — | US | disclosed |
| US-11795165-B2 | Tetrahydro-benzoazepine glycosidase inhibitors | ASCENEURON SA (CH) | 2023-10-24 | — | — | US | disclosed |
| US-11795165-B2 | Tetrahydro-benzoazepine glycosidase inhibitors | ASCENEURON SA (CH) | 2023-10-24 | — | — | US | disclosed |
| US-4985438-A | PSYCHOTROPIC ACTIVITY, ANTIDEPRESSANTS | JOHN WYETH & BROTHER, LIMITED (GB) | 1991-01-15 | — | — | US | disclosed |
| US-4806552-A | ANTIDEPRESSANTS | JOHN WYETH & BROTHER, LIMITED (GB) | 1989-02-21 | — | — | US | disclosed |
| US-4722930-A | ANTIDEPRESSANTS | JOHN WYETH AND BROTHER LIMITED (GB) | 1988-02-02 | — | — | US | disclosed |
| US-4563466-A | ANTISEROTONINE | JOHN WYETH & BROTHER LIMITED (GB) | 1986-01-07 | — | — | US | disclosed |
| EP-0035374-B1 | PIPERIDYL - UREA, - THIOUREA AND - GUANIDINE DERIVATIVES, AND INTERMEDIATES THEREFOR, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE DERIVATIVES | JOHN WYETH & BROTHER LIMITED (GB) | 1985-01-30 | — | — | EP | disclosed |
| US-4426387-A | Piperid-4-yl ureas and thio ureas used as anti-depressant agents | JOHN WYETH & BROTHER LTD. (GB) | 1984-01-17 | — | — | US | disclosed |
| EP-0035374-A2 | Piperidyl - urea, - thiourea and - guanidine derivatives, and intermediates therefor, processes for preparing them and pharmaceutical compositions containing the derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1981-09-09 | — | — | EP | disclosed |
| US-4001339-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3946040-A | JUVENILE HORMONE ACTIVITY, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-03-23 | — | — | US | disclosed |
| US-3944531-A | P-ALKOXY-BENZALDEHYDES, INSECTICIDE | HOFFMANN-LA ROCHE INC. (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092766-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | PDCD1 4728/4885CD274 4726/4885CYP2D6 1127/4885 |
| US-11795165-B2 | Tetrahydro-benzoazepine glycosidase inhibitors | BACE1, BACE2, BCHE | PDCD1 4430/4885CD274 3850/4885CYP2D6 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.