Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.80 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.72 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959346 | 1.00 | AGTR1 (0.80) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6972402 | 0.91 | AGTR1 (0.84) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6972396 | 0.91 | AGTR1 (0.84) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9424168 | 0.89 | AGTR1 (0.64) | AGTR1 | |
| SCHEMBL9424171 | 0.89 | AGTR1 (0.64) | AGTR1 | |
| SCHEMBL6968628 | 0.89 | AGTR1 (0.83) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6968621 | 0.89 | AGTR1 (0.83) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9424395 | 0.88 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL9424402 | 0.88 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL683466 | 0.87 | AGTR1 (0.75) | AGTR1ABCC3ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955294-B1 | Imidazolyl-alkenoic acid | SMITHKLINE BEECHAM CORP (US) | 2003-09-24 | — | — | EP | disclosed |
| EP-0955294-A2 | Imidazolyl-alkenoic acid | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-10 | — | — | EP | disclosed |
| US-5418250-A | Hypotensive | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-23 | — | — | US | disclosed |
| US-5185351-A | Hypotensive agents; for treatment of congestive heart failure, renal failure and glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0403159-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |