Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | MPC2 | O95563 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964931 | 0.87 | PPARG (0.56) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL6964001 | 0.84 | PPARG (0.56) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL377641 | 0.83 | FFAR1 (0.59) | PPARGFFAR1PPARACYP3A4 | |
| SCHEMBL29602962 | 0.83 | FFAR1 (0.59) | PPARGFFAR1PPARACYP3A4 | |
| SCHEMBL6958784 | 0.82 | FFAR1 (0.58) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL6963885 | 0.82 | FFAR1 (0.53) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL6966643 | 0.81 | FFAR1 (0.52) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL6954874 | 0.81 | PPARG (0.63) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL16379095 | 0.81 | PPARG (0.64) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL6960528 | 0.81 | FFAR1 (0.49) | PPARGFFAR1PPARACYP3A4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |