Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.53 |
| ▸ | PPARA | Q07869 | 6/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | MPC2 | O95563 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377641 | 0.91 | FFAR1 (0.59) | FFAR1PPARAPPARGCYP3A4 | |
| SCHEMBL29602962 | 0.91 | FFAR1 (0.59) | FFAR1PPARAPPARGCYP3A4 | |
| SCHEMBL6964661 | 0.89 | FFAR1 (0.51) | FFAR1PPARAPPARGCYP3A4RXRA | |
| SCHEMBL6964001 | 0.89 | PPARG (0.56) | FFAR1PPARAPPARGCYP3A4RXRA | |
| SCHEMBL3969699 | 0.88 | FFAR1 (0.60) | FFAR1PPARAPPARGCYP3A4RXRA | |
| SCHEMBL6958784 | 0.88 | FFAR1 (0.58) | FFAR1PPARAPPARGCYP3A4RXRA | |
| SCHEMBL6956120 | 0.87 | FFAR1 (0.63) | FFAR1PPARAPPARG | |
| SCHEMBL6958822 | 0.86 | FFAR1 (0.52) | FFAR1PPARAPPARGCYP3A4RXRA | |
| SCHEMBL6955783 | 0.85 | FFAR1 (0.48) | FFAR1PPARAPPARGCYP3A4RXRA | |
| SCHEMBL6959296 | 0.85 | FFAR1 (0.51) | FFAR1PPARAPPARGCYP3A4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |