Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149347 | 0.98 | — | — | |
| SCHEMBL29395766 | 0.98 | — | — | |
| SCHEMBL29809066 | 0.95 | TSHR (0.40) | TSHRDRD2DRD3GRIN1GRIN2B | |
| SCHEMBL14958547 | 0.95 | TSHR (0.46) | TSHRDRD2DRD3GRIN1GRIN2B | |
| Ammonia Solution, Strong SCHEMBL28559765 | 0.93 | TSHR (0.39) | TSHRDRD2DRD3GRIN1GRIN2B | |
| SCHEMBL29405362 | 0.93 | TSHR (0.48) | TSHRDRD2DRD3GRIN1GRIN2B | |
| SCHEMBL26989 | 0.93 | TSHR (0.48) | TSHRDRD2DRD3GRIN1GRIN2B | |
| SCHEMBL3991228 | 0.91 | TSHR (0.46) | TSHRDRD2DRD3GRIN1GRIN2B | |
| SCHEMBL830033 | 0.91 | TSHR (0.46) | TSHRDRD2DRD3GRIN1GRIN2B | |
| SCHEMBL30075870 | 0.91 | TSHR (0.46) | TSHRDRD2DRD3GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751486-B2 | Hollow weave fabric for an air bag and method of producing the same | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2017-09-05 | — | — | US | disclosed |
| US-20140220245-A1 | HOLLOW WEAVE FABRIC FOR AN AIR BAG AND METHOD OF PRODUCING THE SAME | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-08-07 | — | — | US | disclosed |
| EP-1770191-B1 | BASE CLOTH FOR HOLLOW-WOVEN AIR BAG AND METHOD FOR PRODUCTION THEREOF | ASAHI KASEI CHEMICALS CORP (JP) | 2013-11-27 | — | — | EP | disclosed |
| EP-2423361-A1 | A hollow weave fabric for an air bag and method of producing the same | Asahi Kasei Chemicals Corporation (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20080042414-A1 | Hollow Weave Fabric for an Air Bag and Method of Producing the Same | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2008-02-21 | — | — | US | disclosed |
| EP-1770191-A1 | BASE CLOTH FOR HOLLOW-WOVEN AIR BAG AND METHOD FOR PRODUCTION THEREOF | Asahi Kasei Chemicals Corporation (JP) | 2007-04-04 | — | — | EP | disclosed |
| US-4555419-A | Method of impregnating textile materials made from organic fibers | WACKER-CHEMIE GMBH (DE) | 1985-11-26 | — | — | US | disclosed |
| US-4481341-A | Thermosetting organopolysiloxane mixtures containing platinum catalyst dispersed in solid silicone resin | BAYER AKTIENGESELLSCHAFT (DE) | 1984-11-06 | — | — | US | disclosed |
| US-4473603-A | ORGANOPOLYSILOXANE CONTAINING SI-BONDED HYDROGEN AND UNSATURATED GROUPS | WACKER-CHEMIE GMBH (DE) | 1984-09-25 | — | — | US | disclosed |