Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR1D | P28221 | 3/20 | 0.53 |
| ▸ | HTR1B | P28222 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | RBP4 | P02753 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966645 | 0.89 | MAPT (0.60) | MAPTRAB9AHTR1AHTR1DHTR1B | |
| SCHEMBL6960630 | 0.87 | LMNA (0.57) | MAPTRAB9AHTR1AHTR1DHTR1B | |
| SCHEMBL8705983 | 0.86 | MAPT (0.57) | MAPTRAB9AHTR1AHTR1DHTR1B | |
| SCHEMBL8699457 | 0.85 | MAPT (0.56) | MAPTRAB9AHTR1AHTR1DHTR1B | |
| SCHEMBL6955171 | 0.85 | MAPT (0.56) | MAPTRAB9AHTR1AHTR1DHTR1B | |
| SCHEMBL6963593 | 0.84 | MAPT (0.54) | MAPTRAB9AHTR1AHTR1DHTR1B | |
| SCHEMBL6966945 | 0.83 | MAPT (0.57) | MAPTRAB9AHTR1AHTR1DHTR1B | |
| SCHEMBL6965181 | 0.83 | MAPT (0.47) | MAPTGAARBP4CA12CA1 | |
| SCHEMBL6653379 | 0.83 | PHGDH (0.57) | MAPTRAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL6960822 | 0.82 | KMT2A (0.42) | MAPTGAARBP4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |