Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 11/20 | 0.53 |
| ▸ | AVPR1B | P47901 | 7/20 | 0.53 |
| ▸ | AVPR2 | P30518 | 12/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969281 | 0.94 | AVPR1A (0.51) | AVPR1AAVPR1BAVPR2PDCD1CD274 | |
| SCHEMBL6970362 | 0.92 | AVPR1A (0.49) | AVPR1AAVPR1BAVPR2PDCD1CD274 | |
| SCHEMBL6970821 | 0.91 | AVPR1A (0.57) | AVPR1AAVPR1BAVPR2PDCD1CD274 | |
| SCHEMBL6957577 | 0.90 | AVPR1A (0.49) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6972648 | 0.89 | AVPR2 (0.49) | AVPR1AAVPR1BAVPR2PDCD1CD274 | |
| SCHEMBL6964451 | 0.89 | AVPR1A (0.49) | AVPR1AAVPR1BAVPR2PDCD1CD274 | |
| SCHEMBL8961772 | 0.87 | AVPR1A (0.54) | AVPR1AAVPR1BAVPR2PDCD1CD274 | |
| SCHEMBL6965230 | 0.86 | AVPR1A (0.56) | AVPR1AAVPR1BAVPR2PDCD1CD274 | |
| SCHEMBL6964131 | 0.86 | MEN1 (0.42) | AVPR1AAVPR1BAVPR2ALDH1A1 | |
| SCHEMBL6970232 | 0.86 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |