Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970606 | 0.91 | AVPR2 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2AVPR1A | |
| SCHEMBL6971575 | 0.90 | AVPR2 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2AVPR1A | |
| SCHEMBL6972648 | 0.88 | AVPR2 (0.49) | AVPR1AAVPR2LMNAAVPR1B | |
| SCHEMBL6960071 | 0.86 | AVPR1A (0.53) | ALDH1A1AVPR1AAVPR2AVPR1B | |
| SCHEMBL6966646 | 0.84 | AVPR1A (0.56) | AVPR1AAVPR2 | |
| SCHEMBL8961719 | 0.82 | AVPR2 (0.47) | AVPR1AAVPR2POLBLMNAMAPT | |
| SCHEMBL6972475 | 0.81 | AVPR2 (0.48) | ALDH1A1AVPR1AAVPR2AVPR1B | |
| SCHEMBL6969281 | 0.81 | AVPR1A (0.51) | AVPR1AAVPR2LMNAAVPR1B | |
| SCHEMBL9414267 | 0.80 | AVPR2 (0.40) | MEN1KMT2AALDH1A1AVPR1AAVPR2 | |
| SCHEMBL6960416 | 0.79 | AVPR1A (0.55) | AVPR1AAVPR2AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |