Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340678 | 0.82 | HDAC4 (0.47) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL460399 | 0.80 | CYP3A4 (0.47) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL824938 | 0.79 | HDAC4 (0.44) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL10552076 | 0.78 | HDAC4 (0.50) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL9858356 | 0.78 | ALDH1A1 (0.46) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL6966273 | 0.78 | — | — | |
| SCHEMBL6049107 | 0.77 | HDAC4 (0.48) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL12795938 | 0.77 | HDAC4 (0.42) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL22324339 | 0.76 | HDAC4 (0.47) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL11805525 | 0.76 | HDAC4 (0.47) | HDAC4HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |